New Releases from NCBI BookshelfStudy into the Reversal of Septic Shock with Beta Blockade (Landiolol): the STRESS-L randomised trial.​Study into the Reversal of Septic Shock with Beta Blockade (Landiolol): the STRESS-L randomised trial.

Autonomic dysfunction and tachycardia are associated with poor outcomes in septic shock. Noradrenaline is recommended to maintain blood pressure but has been associated with harm. Beta-blockade has been associated with improved survival. We hypothesised that beta1 receptor antagonism with landiolol would benefit patients with septic shock through myocardial protection and immunomodulation.

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