New Releases from NCBI BookshelfNIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,4-Dichlorobenzene (CASRN 106-46-7) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 13 [Internet].​NIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,4-Dichlorobenzene (CASRN 106-46-7) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 13 [Internet].

1,4-Dichlorobenzene (1,4-DCB) is a chlorinated aromatic hydrocarbon that is used in various industrial and household applications, including as a fumigant for moth control, a deodorizer in urinal cakes, and an air freshener in domestic and public settings. Short-term in vivo transcriptomic studies were used to assess the biological potency of 1,4-DCB. The data from these studies are intended to support risk assessment and establishment of acceptable exposure levels of 1,4-DCB in environmental and occupational settings.

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