New Releases from NCBI BookshelfNIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,2-Dichlorobenzene (CASRN 95-50-1) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 12 [Internet].​NIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,2-Dichlorobenzene (CASRN 95-50-1) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 12 [Internet].

1,2-Dichlorobenzene (1,2-DCB) is a chlorinated aromatic hydrocarbon that is widely used in industrial applications, including as a solvent for waxes, resins, and paints, and it serves as an ingredient in the production of disinfectants and deodorants. Short-term in vivo transcriptomic studies were used to assess the biological potency of 1,2-DCB. The data from these studies are intended to support risk assessment and establishment of acceptable exposure levels of 1,2-DCB in environmental and occupational settings.

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