New Releases from NCBI BookshelfInavolisib (Itovebi): Indication: Inavolisib in combination with palbociclib and fulvestrant is indicated for the treatment of adult patients with endocrine resistant, PIK3CA-mutated, hormone receptor–positive, human epidermal growth factor receptor 2–negative, locally advanced or metastatic breast cancer, following recurrence on or after completing adjuvant endocrine treatment: Reimbursement Recommendation [Internet].​Inavolisib (Itovebi): Indication: Inavolisib in combination with palbociclib and fulvestrant is indicated for the treatment of adult patients with endocrine resistant, PIK3CA-mutated, hormone receptor–positive, human epidermal growth factor receptor 2–negative, locally advanced or metastatic breast cancer, following recurrence on or after completing adjuvant endocrine treatment: Reimbursement Recommendation [Internet].

Canada’s Drug Agency (CDA-AMC) recommends that Itovebi in combination with palbociclib (PAL) and fulvestrant (FUL) be reimbursed by public drug plans for the treatment of adult patients with endocrine-resistant, PIK3CA-mutated, hormone receptor–positive, HER2-negative, locally advanced or metastatic breast cancer, following recurrence on or after completing adjuvant endocrine treatment, only if certain conditions are met.

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