The Patient-Reported Outcomes Measurement Information System (PROMIS) has not been widely used in clinical practice settings. When we submitted our application, the content validity of PROMIS short forms (ie, static paper questionnaires of fixed length) had not been evaluated in many patients with specific diseases. The expected change in PROMIS scores between clinic visits was unknown. There was little guidance about what was meant when patients reported mild, moderate, and severe symptoms, and how much change would be judged as meaningful from the perspective of patients and providers. In this project we sought to address these gaps in patients with rheumatoid arthritis (RA).
