New Releases from NCBI BookshelfZolbetuximab for Injection (Vyloy): Indication: In combination with fluoropyrimidine- and platinum-containing chemotherapy, is indicated for the first-line treatment of adult patients with locally advanced unresectable or metastatic human epidermal growth factor receptor 2-negative gastric or gastroesophageal junction adenocarcinoma whose tumours are Claudin 18.2 positive: Reimbursement Recommendation [Internet].​Zolbetuximab for Injection (Vyloy): Indication: In combination with fluoropyrimidine- and platinum-containing chemotherapy, is indicated for the first-line treatment of adult patients with locally advanced unresectable or metastatic human epidermal growth factor receptor 2-negative gastric or gastroesophageal junction adenocarcinoma whose tumours are Claudin 18.2 positive: Reimbursement Recommendation [Internet].

Canada’s Drug Agency (CDA-AMC) recommends that Vyloy should be reimbursed by public drug plans for the first-line treatment of adults with locally advanced unresectable or metastatic human epidermal growth factor receptor 2 (HER2)-negative gastric or gastroesophageal junction (GEJ) adenocarcinoma with tumours that are CLDN18.2 positive if certain conditions are met.

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