We conducted this systematic review to support the U.S. Preventive Services Task Force (USPSTF) in updating its recommendations on breast cancer screening. Our review addresses the comparative effectiveness of breast cancer screening for improving health outcomes. The review compares different strategies regarding when to screen (e.g., age to start/stop screening, screening interval), screening modalities (e.g., digital breast tomosynthesis [DBT] versus digital mammography [DM]), supplemental screening, or screening strategies defined by breast cancer risk markers.
