Tobacco use and alcohol use place first and third, respectively, as leading modifiable risk factors for cancer cases and deaths in the US. Our National Cancer Policy Forum convened a public workshop in March 2025 to examine current evidence on the health outcomes of tobacco and alcohol use, including their synergistic effects. Participants explored the state of research on tobacco and alcohol as cancer risk factors and differences in outcomes across U.S. populations. Speakers discussed potential strategies, such as community engagement and public health messaging, to reduce tobacco and alcohol use to lower cancer risk and improve health outcomes for all. This Proceedings of a Workshop summarizes presentations and discussions from the workshop.
