New Releases from NCBI BookshelfElexacaftor-Tezacaftor-Ivacaftor and Ivacaftor (Trikafta): Indication: Treatment of cystic fibrosis in patients aged 2 years and older who have at least one mutation in the CFTR gene that is responsive based on clinical and/or in vitro data: Reimbursement Recommendation [Internet].​Elexacaftor-Tezacaftor-Ivacaftor and Ivacaftor (Trikafta): Indication: Treatment of cystic fibrosis in patients aged 2 years and older who have at least one mutation in the CFTR gene that is responsive based on clinical and/or in vitro data: Reimbursement Recommendation [Internet].

Canada’s Drug Agency (CDA-AMC) recommends that Trikafta be reimbursed by public drug plans for the treatment of cystic fibrosis (CF) in patients aged 2 years and older who have at least 1 of the 152 non-F508del mutations in the CFTR gene that are identified in Figure 1 of this document, if certain conditions are met.

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